BDBM50359360 CHEMBL1929239

SMILES: CN(C)CCN1CCN(CCC1=O)C(=O)c1cc(sc1NC(=O)Nc1ccc(F)c(Cl)c1Cl)C(C)(C)C

InChI Key: InChIKey=JFAYKLGHUXFQQT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359360   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 14 (Homo sapiens (Human))	BDBM50359360 (CHEMBL1929239) Show SMILES CN(C)CCN1CCN(CCC1=O)C(=O)c1cc(sc1NC(=O)Nc1ccc(F)c(Cl)c1Cl)C(C)(C)C Show InChI InChI=1S/C25H32Cl2FN5O3S/c1-25(2,3)18-14-15(23(35)33-9-8-19(34)32(12-13-33)11-10-31(4)5)22(37-18)30-24(36)29-17-7-6-16(28)20(26)21(17)27/h6-7,14H,8-13H2,1-5H3,(H2,29,30,36)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Ansaris Curated by ChEMBL					Assay Description Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into GST-ATF2 substrate preincubated for 20 mins before substrate addition measured a...				Bioorg Med Chem Lett 21: 7155-65 (2011) Article DOI: 10.1016/j.bmcl.2011.09.078 BindingDB Entry DOI: 10.7270/Q2NC61NH
					More data for this Ligand-Target Pair