BDBM50359371 CHEMBL1929392

SMILES: Cc1c(cnc2cc(nn12)-c1ccccc1)C(=O)NCC(C)(C)NCC(=O)N1CCC[C@H]1C#N

InChI Key: InChIKey=ZWYVWOHOVTWLNH-IBGZPJMESA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50359371   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50359371 (CHEMBL1929392) Show SMILES Cc1c(cnc2cc(nn12)-c1ccccc1)C(=O)NCC(C)(C)NCC(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C25H29N7O2/c1-17-20(14-27-22-12-21(30-32(17)22)18-8-5-4-6-9-18)24(34)28-16-25(2,3)29-15-23(33)31-11-7-10-19(31)13-26/h4-6,8-9,12,14,19,29H,7,10-11,15-16H2,1-3H3,(H,28,34)/t19-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Sanwa Kagaku Kenkyusho Co. Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP-4 using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition measured after 20 mins by f...				Bioorg Med Chem 19: 7221-7 (2011) Article DOI: 10.1016/j.bmc.2011.09.043 BindingDB Entry DOI: 10.7270/Q2862GVX
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 9 (Homo sapiens (Human))	BDBM50359371 (CHEMBL1929392) Show SMILES Cc1c(cnc2cc(nn12)-c1ccccc1)C(=O)NCC(C)(C)NCC(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C25H29N7O2/c1-17-20(14-27-22-12-21(30-32(17)22)18-8-5-4-6-9-18)24(34)28-16-25(2,3)29-15-23(33)31-11-7-10-19(31)13-26/h4-6,8-9,12,14,19,29H,7,10-11,15-16H2,1-3H3,(H,28,34)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Sanwa Kagaku Kenkyusho Co. Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP-9 expressed in Sf9 cells using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition meas...				Bioorg Med Chem 19: 7221-7 (2011) Article DOI: 10.1016/j.bmc.2011.09.043 BindingDB Entry DOI: 10.7270/Q2862GVX
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM50359371 (CHEMBL1929392) Show SMILES Cc1c(cnc2cc(nn12)-c1ccccc1)C(=O)NCC(C)(C)NCC(=O)N1CCC[C@H]1C#N |r| Show InChI InChI=1S/C25H29N7O2/c1-17-20(14-27-22-12-21(30-32(17)22)18-8-5-4-6-9-18)24(34)28-16-25(2,3)29-15-23(33)31-11-7-10-19(31)13-26/h4-6,8-9,12,14,19,29H,7,10-11,15-16H2,1-3H3,(H,28,34)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Sanwa Kagaku Kenkyusho Co. Ltd Curated by ChEMBL					Assay Description Inhibition of human recombinant DPP-8 expressed in Sf9 cells using H-Gly-Pro-AMC as substrate preincubated for 30 mins before substrate addition meas...				Bioorg Med Chem 19: 7221-7 (2011) Article DOI: 10.1016/j.bmc.2011.09.043 BindingDB Entry DOI: 10.7270/Q2862GVX
					More data for this Ligand-Target Pair