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BDBM50359405 CHEMBL457349

SMILES: CCOC(=O)Nc1cc(NCCCCN(CC)CC)c2nc(-c3ccccc3)c(nc2n1)-c1ccccc1

InChI Key: InChIKey=JAMASXYVIJBNCE-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359405   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cell division protein FtsZ


(Mycobacterium tuberculosis)		BDBM50359405
PNG
(CHEMBL457349)
Show SMILES CCOC(=O)Nc1cc(NCCCCN(CC)CC)c2nc(-c3ccccc3)c(nc2n1)-c1ccccc1
Show InChI InChI=1S/C30H36N6O2/c1-4-36(5-2)20-14-13-19-31-24-21-25(33-30(37)38-6-3)32-29-28(24)34-26(22-15-9-7-10-16-22)27(35-29)23-17-11-8-12-18-23/h7-12,15-18,21H,4-6,13-14,19-20H2,1-3H3,(H2,31,32,33,35,37)
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Similars
Article
PubMed
n/an/a 5.20E+4n/an/an/an/an/an/a



Southern Research Institute

Curated by ChEMBL


Assay Description
Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay

Bioorg Med Chem 19: 7120-8 (2011)


Article DOI: 10.1016/j.bmc.2011.09.062
BindingDB Entry DOI: 10.7270/Q2VX0GZ1
More data for this
Ligand-Target Pair