BDBM50359408 CHEMBL1926720
SMILES: CCOC(=O)Nc1cc(NCCN(CC)CC)c2nc(-c3ccco3)c(nc2n1)-c1ccco1
InChI Key: InChIKey=GXPHTOWHZAJXME-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cell division protein FtsZ (Mycobacterium tuberculosis) | BDBM50359408 (CHEMBL1926720) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.48E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay | Bioorg Med Chem 19: 7120-8 (2011) Article DOI: 10.1016/j.bmc.2011.09.062 BindingDB Entry DOI: 10.7270/Q2VX0GZ1 | |||||||||||
More data for this Ligand-Target Pair |