BDBM50359414 CHEMBL1926726

SMILES: CCOC(=O)Nc1nc(NC(C)CCCN(CC)CC)c2N=C(C(Sc2n1)c1ccccc1)c1ccccc1

InChI Key: InChIKey=QPAPXDIFCXITEA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50359414   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cell division protein FtsZ (Mycobacterium tuberculosis)	BDBM50359414 (CHEMBL1926726) Show SMILES CCOC(=O)Nc1nc(NC(C)CCCN(CC)CC)c2N=C(C(Sc2n1)c1ccccc1)c1ccccc1 |c:21| Show InChI InChI=1S/C30H38N6O2S/c1-5-36(6-2)20-14-15-21(4)31-27-25-28(34-29(33-27)35-30(37)38-7-3)39-26(23-18-12-9-13-19-23)24(32-25)22-16-10-8-11-17-22/h8-13,16-19,21,26H,5-7,14-15,20H2,1-4H3,(H2,31,33,34,35,37)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Institute Curated by ChEMBL					Assay Description Inhibition of Mycobacterium tuberculosis FtsZ polymerization expressed in Escherichia coli by light scattering assay				Bioorg Med Chem 19: 7120-8 (2011) Article DOI: 10.1016/j.bmc.2011.09.062 BindingDB Entry DOI: 10.7270/Q2VX0GZ1
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