BDBM50359616 CHEMBL1928221
SMILES: O[C@@H](CC1CCCCC1)\C=C\[C@H]1[C@H](O)C[C@@H]2Oc3c(cccc3CCC(O)=O)[C@H]12
InChI Key: InChIKey=UQTNNJRLITVZKP-PQEHKDGBSA-N
Data: 1 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E2 receptor EP4 subtype (Oryctolagus cuniculus) | BDBM50359616 (CHEMBL1928221) | KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 5.70 | n/a | n/a | n/a | n/a |
Toray Industries, Inc. Curated by ChEMBL | Assay Description Agonist activity at rabbit EP4 receptor assessed as relaxation of Kcl-induced tissue contraction by isometric transducer method | Bioorg Med Chem Lett 21: 7505-8 (2011) Article DOI: 10.1016/j.bmcl.2011.09.004 BindingDB Entry DOI: 10.7270/Q2SX6DNT | |||||||||||
More data for this Ligand-Target Pair |