BDBM50359739 CHEMBL1927730
SMILES: Clc1cccc2c1[nH]c(=S)n(-c1ccccc1Br)c2=O
InChI Key: InChIKey=YRCIWNIXJIRLCR-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A (Homo sapiens (Human)) | BDBM50359739 (CHEMBL1927730) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Instituto de Qu£mica M£dica (CSIC) Curated by ChEMBL | Assay Description Inhibition of PDE7A assessed as hydrolysis of [3H]cAMP after 20 mins by scintillation proximity assay | Eur J Med Chem 47: 175-85 (2012) Article DOI: 10.1016/j.ejmech.2011.10.040 BindingDB Entry DOI: 10.7270/Q20G3KJS | |||||||||||
More data for this Ligand-Target Pair |