BDBM50359962 CHEMBL1927096

SMILES: N#CNC(=NCCCN1CCN(CC1)c1ncccn1)c1ccccn1

InChI Key: InChIKey=DLTDRUFHRWCSNO-UHFFFAOYSA-N

Data: 5 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50359962   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50359962 (CHEMBL1927096) Show SMILES N#CNC(=NCCCN1CCN(CC1)c1ncccn1)c1ccccn1 |w:4.4| Show InChI InChI=1S/C18H22N8/c19-15-24-17(16-5-1-2-6-20-16)21-9-4-10-25-11-13-26(14-12-25)18-22-7-3-8-23-18/h1-3,5-8H,4,9-14H2,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.0161	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from Sprague-Dawley rat brain cortex serotonin 5-HT2A receptor after 15 mins by liquid scintillation counting				Eur J Med Chem 47: 520-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.023 BindingDB Entry DOI: 10.7270/Q29S1RFN
					More data for this Ligand-Target Pair
Serotonin receptor 2a and 2c (5HT2A and 5HT2C) (Rattus norvegicus (Rat))	BDBM50359962 (CHEMBL1927096) Show SMILES N#CNC(=NCCCN1CCN(CC1)c1ncccn1)c1ccccn1 |w:4.4| Show InChI InChI=1S/C18H22N8/c19-15-24-17(16-5-1-2-6-20-16)21-9-4-10-25-11-13-26(14-12-25)18-22-7-3-8-23-18/h1-3,5-8H,4,9-14H2,(H,21,24)	KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	22.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine from Sprague-Dawley rat brain cortex serotonin 5-HT2C receptor after 15 mins by liquid scintillation counting in pres...				Eur J Med Chem 47: 520-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.023 BindingDB Entry DOI: 10.7270/Q29S1RFN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50359962 (CHEMBL1927096) Show SMILES N#CNC(=NCCCN1CCN(CC1)c1ncccn1)c1ccccn1 |w:4.4| Show InChI InChI=1S/C18H22N8/c19-15-24-17(16-5-1-2-6-20-16)21-9-4-10-25-11-13-26(14-12-25)18-22-7-3-8-23-18/h1-3,5-8H,4,9-14H2,(H,21,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of [3H]-8-OH-DPAT from Sprague-Dawley rat brain cortex serotonin 5-HT1A receptor after 30 mins by liquid scintillation counting				Eur J Med Chem 47: 520-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.023 BindingDB Entry DOI: 10.7270/Q29S1RFN
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50359962 (CHEMBL1927096) Show SMILES N#CNC(=NCCCN1CCN(CC1)c1ncccn1)c1ccccn1 |w:4.4| Show InChI InChI=1S/C18H22N8/c19-15-24-17(16-5-1-2-6-20-16)21-9-4-10-25-11-13-26(14-12-25)18-22-7-3-8-23-18/h1-3,5-8H,4,9-14H2,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from rat corpora striatum dopamine D2 receptor after 15 mins by liquid scintillation counting				Eur J Med Chem 47: 520-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.023 BindingDB Entry DOI: 10.7270/Q29S1RFN
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50359962 (CHEMBL1927096) Show SMILES N#CNC(=NCCCN1CCN(CC1)c1ncccn1)c1ccccn1 |w:4.4| Show InChI InChI=1S/C18H22N8/c19-15-24-17(16-5-1-2-6-20-16)21-9-4-10-25-11-13-26(14-12-25)18-22-7-3-8-23-18/h1-3,5-8H,4,9-14H2,(H,21,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of [3H]SCH-23390 from rat corpora striatum dopamine D1 receptor after 15 mins by liquid scintillation counting				Eur J Med Chem 47: 520-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.023 BindingDB Entry DOI: 10.7270/Q29S1RFN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50359962 (CHEMBL1927096) Show SMILES N#CNC(=NCCCN1CCN(CC1)c1ncccn1)c1ccccn1 |w:4.4| Show InChI InChI=1S/C18H22N8/c19-15-24-17(16-5-1-2-6-20-16)21-9-4-10-25-11-13-26(14-12-25)18-22-7-3-8-23-18/h1-3,5-8H,4,9-14H2,(H,21,24)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0217	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Napoli"Federico II" Curated by ChEMBL					Assay Description Displacement of [3H]ketanserin from Sprague-Dawley rat brain cortex serotonin 5-HT2A receptor after 15 mins by liquid scintillation counting				Eur J Med Chem 47: 520-9 (2012) Article DOI: 10.1016/j.ejmech.2011.11.023 BindingDB Entry DOI: 10.7270/Q29S1RFN
					More data for this Ligand-Target Pair