null

SMILES: CN(\N=C\c1cnn2ccc(cc12)C#N)C(=O)c1cc(ccc1C)[N+]([O-])=O

InChI Key: InChIKey=CRSVRMFKDICNQP-KEBDBYFISA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50360087   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM50360087 (CHEMBL1928728) Show SMILES CN(\N=C\c1cnn2ccc(cc12)C#N)C(=O)c1cc(ccc1C)[N+]([O-])=O Show InChI InChI=1S/C18H14N6O3/c1-12-3-4-15(24(26)27)8-16(12)18(25)22(2)20-10-14-11-21-23-6-5-13(9-19)7-17(14)23/h3-8,10-11H,1-2H3/b20-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of recombinant PI3K p110alpha using L-alpha-phosphotidylinositol as substrate and [gamma33P]ATP after 60 mins by thin layer chromatographi...				Bioorg Med Chem 20: 58-68 (2011) Article DOI: 10.1016/j.bmc.2011.11.031 BindingDB Entry DOI: 10.7270/Q21C1X99
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM50360087 (CHEMBL1928728) Show SMILES CN(\N=C\c1cnn2ccc(cc12)C#N)C(=O)c1cc(ccc1C)[N+]([O-])=O Show InChI InChI=1S/C18H14N6O3/c1-12-3-4-15(24(26)27)8-16(12)18(25)22(2)20-10-14-11-21-23-6-5-13(9-19)7-17(14)23/h3-8,10-11H,1-2H3/b20-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of recombinant PI3K p110delta using L-alpha-phosphotidylinositol as substrate and [gamma33P]ATP after 60 mins by thin layer chromatographi...				Bioorg Med Chem 20: 58-68 (2011) Article DOI: 10.1016/j.bmc.2011.11.031 BindingDB Entry DOI: 10.7270/Q21C1X99
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (Homo sapiens (Human))	BDBM50360087 (CHEMBL1928728) Show SMILES CN(\N=C\c1cnn2ccc(cc12)C#N)C(=O)c1cc(ccc1C)[N+]([O-])=O Show InChI InChI=1S/C18H14N6O3/c1-12-3-4-15(24(26)27)8-16(12)18(25)22(2)20-10-14-11-21-23-6-5-13(9-19)7-17(14)23/h3-8,10-11H,1-2H3/b20-10+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
University of Auckland Curated by ChEMBL					Assay Description Inhibition of recombinant PI3K p110beta using L-alpha-phosphotidylinositol as substrate and [gamma33P]ATP after 60 mins by thin layer chromatographic...				Bioorg Med Chem 20: 58-68 (2011) Article DOI: 10.1016/j.bmc.2011.11.031 BindingDB Entry DOI: 10.7270/Q21C1X99
					More data for this Ligand-Target Pair