BDBM50360165 CHEMBL1929532
SMILES: CCCc1cccc(C[C@H](O)\C=C\[C@H]2COC(=O)N2CCSCCCC(O)=O)c1
InChI Key: InChIKey=PHPSNQYNGUADLO-ILXKITPQSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Prostanoid EP4 Receptor (Mus musculus (Mouse)) | BDBM50360165 (CHEMBL1929532) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP4 receptor expressed in CHO cells after 60 mins by liquid scintillation counter | Bioorg Med Chem 20: 702-13 (2012) Checked by Author Article DOI: 10.1016/j.bmc.2011.12.009 BindingDB Entry DOI: 10.7270/Q2CJ8DXN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP3 Receptor (Mus musculus (Mouse)) | BDBM50360165 (CHEMBL1929532) | UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP3 receptor expressed in CHO cells after 60 mins by liquid scintillation counter | Bioorg Med Chem 20: 702-13 (2012) Checked by Author Article DOI: 10.1016/j.bmc.2011.12.009 BindingDB Entry DOI: 10.7270/Q2CJ8DXN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP1 Receptor (Mus musculus (Mouse)) | BDBM50360165 (CHEMBL1929532) | Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP1 receptor expressed in CHO cells after 20 mins by liquid scintillation counter | Bioorg Med Chem 20: 702-13 (2012) Checked by Author Article DOI: 10.1016/j.bmc.2011.12.009 BindingDB Entry DOI: 10.7270/Q2CJ8DXN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP2 Receptor (Mus musculus (Mouse)) | BDBM50360165 (CHEMBL1929532) | PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Displacement of [3H]-PGE2 from mouse EP2 receptor expressed in CHO cells after 60 mins by liquid scintillation counter | Bioorg Med Chem 20: 702-13 (2012) Checked by Author Article DOI: 10.1016/j.bmc.2011.12.009 BindingDB Entry DOI: 10.7270/Q2CJ8DXN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Prostanoid EP4 receptor (Rattus norvegicus) | BDBM50360165 (CHEMBL1929532) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 93 | n/a | n/a | n/a | n/a |
Minase Research Institute Curated by ChEMBL | Assay Description Agonist activity at rat EP4 receptor expressed in CHO cells assessed as cAMP production after 10 mins by radioimmunoassay | Bioorg Med Chem 20: 702-13 (2012) Checked by Author Article DOI: 10.1016/j.bmc.2011.12.009 BindingDB Entry DOI: 10.7270/Q2CJ8DXN | |||||||||||
More data for this Ligand-Target Pair |