BDBM50360284 CHEMBL1933068::US9150577, 198

SMILES: O=C(Nc1cc(no1)C1CC1)c1ccc2cc3C(=O)NCCCn3c2c1

InChI Key: InChIKey=UJAUSTYSRUCHNY-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50360284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha 2 (Homo sapiens (Human))	BDBM50360284 (CHEMBL1933068 | US9150577, 198) Show SMILES O=C(Nc1cc(no1)C1CC1)c1ccc2cc3C(=O)NCCCn3c2c1 Show InChI InChI=1S/C19H18N4O3/c24-18(21-17-10-14(22-26-17)11-2-3-11)13-5-4-12-8-16-19(25)20-6-1-7-23(16)15(12)9-13/h4-5,8-11H,1-3,6-7H2,(H,20,25)(H,21,24)	Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...				US Patent US9150577 (2015) BindingDB Entry DOI: 10.7270/Q2GB22V6
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50360284 (CHEMBL1933068 | US9150577, 198) Show SMILES O=C(Nc1cc(no1)C1CC1)c1ccc2cc3C(=O)NCCCn3c2c1 Show InChI InChI=1S/C19H18N4O3/c24-18(21-17-10-14(22-26-17)11-2-3-11)13-5-4-12-8-16-19(25)20-6-1-7-23(16)15(12)9-13/h4-5,8-11H,1-3,6-7H2,(H,20,25)(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer-Ingelheim Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of human RSK2				Bioorg Med Chem Lett 22: 738-42 (2011) Article DOI: 10.1016/j.bmcl.2011.10.029 BindingDB Entry DOI: 10.7270/Q2348KTR
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50360284 (CHEMBL1933068 | US9150577, 198) Show SMILES O=C(Nc1cc(no1)C1CC1)c1ccc2cc3C(=O)NCCCn3c2c1 Show InChI InChI=1S/C19H18N4O3/c24-18(21-17-10-14(22-26-17)11-2-3-11)13-5-4-12-8-16-19(25)20-6-1-7-23(16)15(12)9-13/h4-5,8-11H,1-3,6-7H2,(H,20,25)(H,21,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer-Ingelheim Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of human RSK2-mediated CREB phosphorylation in HLR-CREB cells by cell based assay				Bioorg Med Chem Lett 22: 738-42 (2011) Article DOI: 10.1016/j.bmcl.2011.10.029 BindingDB Entry DOI: 10.7270/Q2348KTR
					More data for this Ligand-Target Pair