BDBM50360473 CHEMBL1934749

SMILES: CCCCN(CC)c1nc(C)nc2n(c(CO)c(C)c12)-c1c(C)cc(C)cc1C

InChI Key: InChIKey=WIBXXGBZSZMQRN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360473   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50360473 (CHEMBL1934749) Show SMILES CCCCN(CC)c1nc(C)nc2n(c(CO)c(C)c12)-c1c(C)cc(C)cc1C |(51.18,-11.74,;52.51,-10.97,;53.85,-11.74,;55.18,-10.97,;56.51,-11.74,;57.85,-10.97,;57.85,-9.43,;56.51,-13.28,;55.18,-14.06,;55.18,-15.6,;53.85,-16.37,;56.51,-16.36,;57.85,-15.6,;59.31,-16.06,;60.21,-14.82,;61.75,-14.81,;62.51,-13.47,;59.3,-13.58,;59.77,-12.11,;57.84,-14.06,;59.79,-17.52,;61.3,-17.83,;62.32,-16.68,;61.78,-19.29,;60.76,-20.45,;61.24,-21.91,;59.25,-20.13,;58.77,-18.67,;57.26,-18.36,)| Show InChI InChI=1S/C24H34N4O/c1-8-10-11-27(9-2)23-21-18(6)20(14-29)28(24(21)26-19(7)25-23)22-16(4)12-15(3)13-17(22)5/h12-13,29H,8-11,14H2,1-7H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells by cAMP assay				Bioorg Med Chem Lett 22: 723-8 (2011) Article DOI: 10.1016/j.bmcl.2011.10.066 BindingDB Entry DOI: 10.7270/Q2J67HCF
					More data for this Ligand-Target Pair