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BDBM50360608 CHEMBL1933072

SMILES: Fc1ccc2[nH]c(cc2c1)C(=O)N1C[C@]2(CCN(CC3CCCNC3)C2)c2ccccc12

InChI Key: InChIKey=VCFBUZYRXPVGQV-WQGFSJIWSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360608   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Syk protein


(Mus musculus)
BDBM50360608
PNG
(CHEMBL1933072)
Show SMILES Fc1ccc2[nH]c(cc2c1)C(=O)N1C[C@]2(CCN(CC3CCCNC3)C2)c2ccccc12 |r|
Show InChI InChI=1S/C26H29FN4O/c27-20-7-8-22-19(12-20)13-23(29-22)25(32)31-17-26(21-5-1-2-6-24(21)31)9-11-30(16-26)15-18-4-3-10-28-14-18/h1-2,5-8,12-13,18,28-29H,3-4,9-11,14-17H2/t18?,26-/m1/s1
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.41E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISA


Bioorg Med Chem Lett 22: 190-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.11.036
BindingDB Entry DOI: 10.7270/Q2CF9QJS
More data for this
Ligand-Target Pair