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BDBM50360617 CHEMBL1933546

SMILES: COc1ccc2cc([nH]c2c1)C(=O)N1C[C@]2(CCN(C2)C2CCNC2)c2ccccc12

InChI Key: InChIKey=DKUGOQDRNOECQX-IXXGTQFESA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360617   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Syk protein


(Mus musculus)
BDBM50360617
PNG
(CHEMBL1933546)
Show SMILES COc1ccc2cc([nH]c2c1)C(=O)N1C[C@]2(CCN(C2)C2CCNC2)c2ccccc12 |r|
Show InChI InChI=1S/C25H28N4O2/c1-31-19-7-6-17-12-22(27-21(17)13-19)24(30)29-16-25(20-4-2-3-5-23(20)29)9-11-28(15-25)18-8-10-26-14-18/h2-7,12-13,18,26-27H,8-11,14-16H2,1H3/t18?,25-/m1/s1
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 843n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISA


Bioorg Med Chem Lett 22: 190-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.11.036
BindingDB Entry DOI: 10.7270/Q2CF9QJS
More data for this
Ligand-Target Pair