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BDBM50360618 CHEMBL1933547

SMILES: NC(=O)c1ccc2cc([nH]c2c1)C(=O)N1C[C@]2(CCN(C2)C2CCNC2)c2ccccc12

InChI Key: InChIKey=ATTQMMYACVSETC-IXXGTQFESA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360618   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Syk protein


(Mus musculus)
BDBM50360618
PNG
(CHEMBL1933547)
Show SMILES NC(=O)c1ccc2cc([nH]c2c1)C(=O)N1C[C@]2(CCN(C2)C2CCNC2)c2ccccc12 |r|
Show InChI InChI=1S/C25H27N5O2/c26-23(31)17-6-5-16-11-21(28-20(16)12-17)24(32)30-15-25(19-3-1-2-4-22(19)30)8-10-29(14-25)18-7-9-27-13-18/h1-6,11-12,18,27-28H,7-10,13-15H2,(H2,26,31)/t18?,25-/m1/s1
PDB
MMDB

KEGG

UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.20E+3n/an/an/an/an/an/a



Pfizer Inc.

Curated by ChEMBL


Assay Description
Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISA


Bioorg Med Chem Lett 22: 190-3 (2011)


Article DOI: 10.1016/j.bmcl.2011.11.036
BindingDB Entry DOI: 10.7270/Q2CF9QJS
More data for this
Ligand-Target Pair