BDBM50360618 CHEMBL1933547

SMILES: NC(=O)c1ccc2cc([nH]c2c1)C(=O)N1C[C@]2(CCN(C2)C2CCNC2)c2ccccc12

InChI Key: InChIKey=ATTQMMYACVSETC-IXXGTQFESA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360618   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Syk protein (Mus musculus)	BDBM50360618 (CHEMBL1933547) Show SMILES NC(=O)c1ccc2cc([nH]c2c1)C(=O)N1C[C@]2(CCN(C2)C2CCNC2)c2ccccc12 |r| Show InChI InChI=1S/C25H27N5O2/c26-23(31)17-6-5-16-11-21(28-20(16)12-17)24(32)30-15-25(19-3-1-2-4-22(19)30)8-10-29(14-25)18-7-9-27-13-18/h1-6,11-12,18,27-28H,7-10,13-15H2,(H2,26,31)/t18?,25-/m1/s1	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. Curated by ChEMBL					Assay Description Inhibition of mouse Sky kinase assessed as inhibition of src substrate phosphorylation by ELISA				Bioorg Med Chem Lett 22: 190-3 (2011) Article DOI: 10.1016/j.bmcl.2011.11.036 BindingDB Entry DOI: 10.7270/Q2CF9QJS
					More data for this Ligand-Target Pair