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SMILES: O[C@@H]1Cc2ccccc2C11CCN(Cc2ccc3[nH]c4ccccc4c3c2)CC1

InChI Key: InChIKey=YFFSPSDGYBLKMB-RUZDIDTESA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360697   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 2


(Homo sapiens (Human))		BDBM50360697
PNG
(CHEMBL1934116)
Show SMILES O[C@@H]1Cc2ccccc2C11CCN(Cc2ccc3[nH]c4ccccc4c3c2)CC1 |r|
Show InChI InChI=1S/C26H26N2O/c29-25-16-19-5-1-3-7-22(19)26(25)11-13-28(14-12-26)17-18-9-10-24-21(15-18)20-6-2-4-8-23(20)27-24/h1-10,15,25,27,29H,11-14,16-17H2/t25-/m1/s1
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n/an/a 10n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...

Bioorg Med Chem Lett 22: 363-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.125
BindingDB Entry DOI: 10.7270/Q2VD6ZW1
More data for this
Ligand-Target Pair