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SMILES: CCn1c2ccccc2c2cc(CN3CCC4(CC3)[C@@H](O)[C@@H](O)c3ccccc43)ccc12

InChI Key: InChIKey=ARCLLIFCIKHDHP-SVBPBHIXSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360705   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 2


(Homo sapiens (Human))		BDBM50360705
PNG
(CHEMBL1934124)
Show SMILES CCn1c2ccccc2c2cc(CN3CCC4(CC3)[C@@H](O)[C@@H](O)c3ccccc43)ccc12 |r|
Show InChI InChI=1S/C28H30N2O2/c1-2-30-24-10-6-4-7-20(24)22-17-19(11-12-25(22)30)18-29-15-13-28(14-16-29)23-9-5-3-8-21(23)26(31)27(28)32/h3-12,17,26-27,31-32H,2,13-16,18H2,1H3/t26-,27-/m0/s1
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n/an/a 250n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...

Bioorg Med Chem Lett 22: 363-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.125
BindingDB Entry DOI: 10.7270/Q2VD6ZW1
More data for this
Ligand-Target Pair