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SMILES: CC(=O)N[C@@H]1CC2(CCN(Cc3ccc4[nH]c5ccc(F)cc5c4c3)CC2)c2ccccc12

InChI Key: InChIKey=BIJXIXLVCDMUDB-HHHXNRCGSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360707   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 2


(Homo sapiens (Human))		BDBM50360707
PNG
(CHEMBL1934126)
Show SMILES CC(=O)N[C@@H]1CC2(CCN(Cc3ccc4[nH]c5ccc(F)cc5c4c3)CC2)c2ccccc12 |r|
Show InChI InChI=1S/C28H28FN3O/c1-18(33)30-27-16-28(24-5-3-2-4-21(24)27)10-12-32(13-11-28)17-19-6-8-25-22(14-19)23-15-20(29)7-9-26(23)31-25/h2-9,14-15,27,31H,10-13,16-17H2,1H3,(H,30,33)/t27-/m1/s1
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Article
PubMed
n/an/a 10n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...

Bioorg Med Chem Lett 22: 363-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.125
BindingDB Entry DOI: 10.7270/Q2VD6ZW1
More data for this
Ligand-Target Pair