Found 3 hits for monomerid = 50360708 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Melanin-concentrating hormone receptor 2
(Homo sapiens (Human)) | BDBM50360708
(CHEMBL1934127)Show SMILES CC(=O)N[C@@H]1CC2(CCN(Cc3ccc4[nH]c5ccc(Cl)cc5c4c3)CC2)c2ccccc12 |r| Show InChI InChI=1S/C28H28ClN3O/c1-18(33)30-27-16-28(24-5-3-2-4-21(24)27)10-12-32(13-11-28)17-19-6-8-25-22(14-19)23-15-20(29)7-9-26(23)31-25/h2-9,14-15,27,31H,10-13,16-17H2,1H3,(H,30,33)/t27-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ... |
Bioorg Med Chem Lett 22: 363-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.125 BindingDB Entry DOI: 10.7270/Q2VD6ZW1 |
More data for this Ligand-Target Pair | |
Sodium-dependent serotonin transporter
(Homo sapiens (Human)) | BDBM50360708
(CHEMBL1934127)Show SMILES CC(=O)N[C@@H]1CC2(CCN(Cc3ccc4[nH]c5ccc(Cl)cc5c4c3)CC2)c2ccccc12 |r| Show InChI InChI=1S/C28H28ClN3O/c1-18(33)30-27-16-28(24-5-3-2-4-21(24)27)10-12-32(13-11-28)17-19-6-8-25-22(14-19)23-15-20(29)7-9-26(23)31-25/h2-9,14-15,27,31H,10-13,16-17H2,1H3,(H,30,33)/t27-/m1/s1 | PDB
KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description Inhibition of serotonin transporter |
Bioorg Med Chem Lett 22: 363-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.125 BindingDB Entry DOI: 10.7270/Q2VD6ZW1 |
More data for this Ligand-Target Pair | |
D(2) dopamine receptor
(Homo sapiens (Human)) | BDBM50360708
(CHEMBL1934127)Show SMILES CC(=O)N[C@@H]1CC2(CCN(Cc3ccc4[nH]c5ccc(Cl)cc5c4c3)CC2)c2ccccc12 |r| Show InChI InChI=1S/C28H28ClN3O/c1-18(33)30-27-16-28(24-5-3-2-4-21(24)27)10-12-32(13-11-28)17-19-6-8-25-22(14-19)23-15-20(29)7-9-26(23)31-25/h2-9,14-15,27,31H,10-13,16-17H2,1H3,(H,30,33)/t27-/m1/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Amgen Inc.
Curated by ChEMBL
| Assay Description Inhibition of dopamine D2 receptor |
Bioorg Med Chem Lett 22: 363-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.10.125 BindingDB Entry DOI: 10.7270/Q2VD6ZW1 |
More data for this Ligand-Target Pair | |