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SMILES: CCn1c2ccccc2c2cc(CN3CCC4(CC(O)c5ccccc45)CC3)ccc12

InChI Key: InChIKey=RGONDGBXSBUYKY-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360711   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor 2


(Homo sapiens (Human))		BDBM50360711
PNG
(CHEMBL1934115)
Show SMILES CCn1c2ccccc2c2cc(CN3CCC4(CC(O)c5ccccc45)CC3)ccc12
Show InChI InChI=1S/C28H30N2O/c1-2-30-25-10-6-4-7-21(25)23-17-20(11-12-26(23)30)19-29-15-13-28(14-16-29)18-27(31)22-8-3-5-9-24(22)28/h3-12,17,27,31H,2,13-16,18-19H2,1H3
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n/an/a 200n/an/an/an/an/an/a



Amgen Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human MCHR2 receptor expressed in CHO cells assessed as inhibition of MCH-stimulated Ca2+ flux preincubated for 10 mins prior ...

Bioorg Med Chem Lett 22: 363-6 (2011)


Article DOI: 10.1016/j.bmcl.2011.10.125
BindingDB Entry DOI: 10.7270/Q2VD6ZW1
More data for this
Ligand-Target Pair