BDBM50360815 CHEMBL1934793
SMILES: Clc1ccc(cc1)-c1nc2c(cnc3cc(Br)ccc23)[nH]1
InChI Key: InChIKey=LQZLGYSSMDMQJY-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prostaglandin E synthase (Homo sapiens (Human)) | BDBM50360815 (CHEMBL1934793) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL | Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay | Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN | |||||||||||
More data for this Ligand-Target Pair |