BDBM50360825 CHEMBL1934803

SMILES: CN(C)c1ccccc1-c1nc2c(cnc3cc(Br)ccc23)[nH]1

InChI Key: InChIKey=QJSPTDMRGSOWCK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50360825   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E synthase (Homo sapiens (Human))	BDBM50360825 (CHEMBL1934803) Show SMILES CN(C)c1ccccc1-c1nc2c(cnc3cc(Br)ccc23)[nH]1 Show InChI InChI=1S/C18H15BrN4/c1-23(2)16-6-4-3-5-13(16)18-21-15-10-20-14-9-11(19)7-8-12(14)17(15)22-18/h3-10H,1-2H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Dainippon Sumitomo Pharma. Co. Ltd Curated by ChEMBL					Assay Description Inhibition of microsomal PGES1 transfected in human HEK293 cells assessed as PGE2 production after 60 mins by HTRF assay				Bioorg Med Chem Lett 22: 285-8 (2011) Article DOI: 10.1016/j.bmcl.2011.11.015 BindingDB Entry DOI: 10.7270/Q2PR7WFN
					More data for this Ligand-Target Pair