Found 9 hits for monomerid = 50360902 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50360902
(CHEMBL1935114)Show SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)C1=NNC(=O)C(C)(C)C1 |r,t:18| Show InChI InChI=1S/C20H29N3O2/c1-15-6-4-11-23(15)12-5-13-25-17-9-7-16(8-10-17)18-14-20(2,3)19(24)22-21-18/h7-10,15H,4-6,11-14H2,1-3H3,(H,22,24)/t15-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 4.30 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from human histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 194-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.037 BindingDB Entry DOI: 10.7270/Q25Q4WJV |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Rattus norvegicus (rat)) | BDBM50360902
(CHEMBL1935114)Show SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)C1=NNC(=O)C(C)(C)C1 |r,t:18| Show InChI InChI=1S/C20H29N3O2/c1-15-6-4-11-23(15)12-5-13-25-17-9-7-16(8-10-17)18-14-20(2,3)19(24)22-21-18/h7-10,15H,4-6,11-14H2,1-3H3,(H,22,24)/t15-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Displacement of [3H]NAMH from rat histamine H3 receptor expressed in CHO cells |
Bioorg Med Chem Lett 22: 194-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.037 BindingDB Entry DOI: 10.7270/Q25Q4WJV |
More data for this Ligand-Target Pair | |
Potassium voltage-gated channel subfamily H member 2
(Homo sapiens (Human)) | BDBM50360902
(CHEMBL1935114)Show SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)C1=NNC(=O)C(C)(C)C1 |r,t:18| Show InChI InChI=1S/C20H29N3O2/c1-15-6-4-11-23(15)12-5-13-25-17-9-7-16(8-10-17)18-14-20(2,3)19(24)22-21-18/h7-10,15H,4-6,11-14H2,1-3H3,(H,22,24)/t15-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of human ERG by patch-express assay |
Bioorg Med Chem Lett 22: 194-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.037 BindingDB Entry DOI: 10.7270/Q25Q4WJV |
More data for this Ligand-Target Pair | |
Cytochrome P450 2C19
(Homo sapiens (Human)) | BDBM50360902
(CHEMBL1935114)Show SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)C1=NNC(=O)C(C)(C)C1 |r,t:18| Show InChI InChI=1S/C20H29N3O2/c1-15-6-4-11-23(15)12-5-13-25-17-9-7-16(8-10-17)18-14-20(2,3)19(24)22-21-18/h7-10,15H,4-6,11-14H2,1-3H3,(H,22,24)/t15-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of CYP2C19 |
Bioorg Med Chem Lett 22: 194-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.037 BindingDB Entry DOI: 10.7270/Q25Q4WJV |
More data for this Ligand-Target Pair | |
Cytochrome P450 2D6
(Homo sapiens (Human)) | BDBM50360902
(CHEMBL1935114)Show SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)C1=NNC(=O)C(C)(C)C1 |r,t:18| Show InChI InChI=1S/C20H29N3O2/c1-15-6-4-11-23(15)12-5-13-25-17-9-7-16(8-10-17)18-14-20(2,3)19(24)22-21-18/h7-10,15H,4-6,11-14H2,1-3H3,(H,22,24)/t15-/m1/s1 | PDB
UniProtKB/SwissProt UniProtKB/TrEMBL
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of CYP2D6 |
Bioorg Med Chem Lett 22: 194-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.037 BindingDB Entry DOI: 10.7270/Q25Q4WJV |
More data for this Ligand-Target Pair | |
Cytochrome P450 3A4
(Homo sapiens (Human)) | BDBM50360902
(CHEMBL1935114)Show SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)C1=NNC(=O)C(C)(C)C1 |r,t:18| Show InChI InChI=1S/C20H29N3O2/c1-15-6-4-11-23(15)12-5-13-25-17-9-7-16(8-10-17)18-14-20(2,3)19(24)22-21-18/h7-10,15H,4-6,11-14H2,1-3H3,(H,22,24)/t15-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of CYP3A4 |
Bioorg Med Chem Lett 22: 194-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.037 BindingDB Entry DOI: 10.7270/Q25Q4WJV |
More data for this Ligand-Target Pair | |
Cytochrome P450 1A
(Homo sapiens (Human)) | BDBM50360902
(CHEMBL1935114)Show SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)C1=NNC(=O)C(C)(C)C1 |r,t:18| Show InChI InChI=1S/C20H29N3O2/c1-15-6-4-11-23(15)12-5-13-25-17-9-7-16(8-10-17)18-14-20(2,3)19(24)22-21-18/h7-10,15H,4-6,11-14H2,1-3H3,(H,22,24)/t15-/m1/s1 | PDB MMDB
Reactome pathway KEGG
B.MOAD DrugBank GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of CYP1A2 |
Bioorg Med Chem Lett 22: 194-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.037 BindingDB Entry DOI: 10.7270/Q25Q4WJV |
More data for this Ligand-Target Pair | |
Histamine H3 receptor
(Homo sapiens (Human)) | BDBM50360902
(CHEMBL1935114)Show SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)C1=NNC(=O)C(C)(C)C1 |r,t:18| Show InChI InChI=1S/C20H29N3O2/c1-15-6-4-11-23(15)12-5-13-25-17-9-7-16(8-10-17)18-14-20(2,3)19(24)22-21-18/h7-10,15H,4-6,11-14H2,1-3H3,(H,22,24)/t15-/m1/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 0.730 | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inverse agonist activity at human histamine H3 receptor by [35S]GTPgammaS binding assay |
Bioorg Med Chem Lett 22: 194-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.037 BindingDB Entry DOI: 10.7270/Q25Q4WJV |
More data for this Ligand-Target Pair | |
Cytochrome P450 2C9
(Homo sapiens (Human)) | BDBM50360902
(CHEMBL1935114)Show SMILES C[C@@H]1CCCN1CCCOc1ccc(cc1)C1=NNC(=O)C(C)(C)C1 |r,t:18| Show InChI InChI=1S/C20H29N3O2/c1-15-6-4-11-23(15)12-5-13-25-17-9-7-16(8-10-17)18-14-20(2,3)19(24)22-21-18/h7-10,15H,4-6,11-14H2,1-3H3,(H,22,24)/t15-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt UniProtKB/TrEMBL
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | >3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Cephalon, Inc.
Curated by ChEMBL
| Assay Description Inhibition of CYP2C9 |
Bioorg Med Chem Lett 22: 194-8 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.037 BindingDB Entry DOI: 10.7270/Q25Q4WJV |
More data for this Ligand-Target Pair | |