BDBM50361029 CHEMBL1935565

SMILES: CN1CCN(CC1)c1nc(N)nc2cc(Br)ccc12

InChI Key: InChIKey=KFXFTLIETQDBCL-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361029   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50361029 (CHEMBL1935565) Show SMILES CN1CCN(CC1)c1nc(N)nc2cc(Br)ccc12 Show InChI InChI=1S/C13H16BrN5/c1-18-4-6-19(7-5-18)12-10-3-2-9(14)8-11(10)16-13(15)17-12/h2-3,8H,4-7H2,1H3,(H2,15,16,17)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffin Discoveries BV Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human H4 receptor expressed in HEK cell membranes				Bioorg Med Chem Lett 22: 461-7 (2011) Article DOI: 10.1016/j.bmcl.2011.10.104 BindingDB Entry DOI: 10.7270/Q2D79BT2
					More data for this Ligand-Target Pair