BDBM50361033 CHEMBL1935569

SMILES: COc1ccc(cc1)-c1ccc2c(nc(N)nc2c1)N1CCN(C)CC1

InChI Key: InChIKey=CPQXBQUJESTPCP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361033   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H4 receptor (Homo sapiens (Human))	BDBM50361033 (CHEMBL1935569) Show SMILES COc1ccc(cc1)-c1ccc2c(nc(N)nc2c1)N1CCN(C)CC1 Show InChI InChI=1S/C20H23N5O/c1-24-9-11-25(12-10-24)19-17-8-5-15(13-18(17)22-20(21)23-19)14-3-6-16(26-2)7-4-14/h3-8,13H,9-12H2,1-2H3,(H2,21,22,23)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Griffin Discoveries BV Curated by ChEMBL					Assay Description Displacement of [3H]histamine from human H4 receptor expressed in HEK cell membranes				Bioorg Med Chem Lett 22: 461-7 (2011) Article DOI: 10.1016/j.bmcl.2011.10.104 BindingDB Entry DOI: 10.7270/Q2D79BT2
					More data for this Ligand-Target Pair