BDBM50361054 CHEMBL1935600

SMILES: Fc1cccc(c1)S(=O)(=O)c1ccc2c3CCNC4(CCOC4)c3oc2c1

InChI Key: InChIKey=BWJSQXMXWCOSKA-UHFFFAOYSA-N

Data: 2 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50361054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50361054 (CHEMBL1935600) Show SMILES Fc1cccc(c1)S(=O)(=O)c1ccc2c3CCNC4(CCOC4)c3oc2c1 Show InChI InChI=1S/C20H18FNO4S/c21-13-2-1-3-14(10-13)27(23,24)15-4-5-16-17-6-8-22-20(7-9-25-12-20)19(17)26-18(16)11-15/h1-5,10-11,22H,6-9,12H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]LSD from full length human 5HT6 receptor				Bioorg Med Chem Lett 22: 120-3 (2011) Article DOI: 10.1016/j.bmcl.2011.11.050 BindingDB Entry DOI: 10.7270/Q24Q7VFX
					More data for this Ligand-Target Pair
HTR6 (RAT)	BDBM50361054 (CHEMBL1935600) Show SMILES Fc1cccc(c1)S(=O)(=O)c1ccc2c3CCNC4(CCOC4)c3oc2c1 Show InChI InChI=1S/C20H18FNO4S/c21-13-2-1-3-14(10-13)27(23,24)15-4-5-16-17-6-8-22-20(7-9-25-12-20)19(17)26-18(16)11-15/h1-5,10-11,22H,6-9,12H2	Reactome pathway UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	132	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]LSD from full length rat 5HT6 receptor				Bioorg Med Chem Lett 22: 120-3 (2011) Article DOI: 10.1016/j.bmcl.2011.11.050 BindingDB Entry DOI: 10.7270/Q24Q7VFX
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50361054 (CHEMBL1935600) Show SMILES Fc1cccc(c1)S(=O)(=O)c1ccc2c3CCNC4(CCOC4)c3oc2c1 Show InChI InChI=1S/C20H18FNO4S/c21-13-2-1-3-14(10-13)27(23,24)15-4-5-16-17-6-8-22-20(7-9-25-12-20)19(17)26-18(16)11-15/h1-5,10-11,22H,6-9,12H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Cephalon, Inc. Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5-HT6 receptor expressed human astrocytoma cells assessed as inhibition of 5-HT-induced cAMP accumulation af...				Bioorg Med Chem Lett 22: 120-3 (2011) Article DOI: 10.1016/j.bmcl.2011.11.050 BindingDB Entry DOI: 10.7270/Q24Q7VFX
					More data for this Ligand-Target Pair