BDBM50361189 CHEMBL1934320

SMILES: CN1CCC(COc2ccc3c(Nc4ccc(CC(=O)Nc5ccc(Cl)c(c5)C(F)(F)F)cc4)ncnc3c2)CC1

InChI Key: InChIKey=RWQHHBVPPXSPNM-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361189   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50361189 (CHEMBL1934320) Show SMILES CN1CCC(COc2ccc3c(Nc4ccc(CC(=O)Nc5ccc(Cl)c(c5)C(F)(F)F)cc4)ncnc3c2)CC1 Show InChI InChI=1S/C30H29ClF3N5O2/c1-39-12-10-20(11-13-39)17-41-23-7-8-24-27(16-23)35-18-36-29(24)38-21-4-2-19(3-5-21)14-28(40)37-22-6-9-26(31)25(15-22)30(32,33)34/h2-9,15-16,18,20H,10-14,17H2,1H3,(H,37,40)(H,35,36,38)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	87	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human GST-tagged VEGFR2 intracellular domain using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 as substrate after 30 mins by HTRF assay				Bioorg Med Chem Lett 22: 110-4 (2011) Article DOI: 10.1016/j.bmcl.2011.11.061 BindingDB Entry DOI: 10.7270/Q2H132FD
					More data for this Ligand-Target Pair