BDBM50361198 CHEMBL1934329

SMILES: CN1CCC(COc2ccc3c(Nc4ccc(NC(=O)Nc5ccc(C)c(Br)c5)cc4)ncnc3c2)CC1

InChI Key: InChIKey=VXYDTDVKGBVVIZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50361198 (CHEMBL1934329) Show SMILES CN1CCC(COc2ccc3c(Nc4ccc(NC(=O)Nc5ccc(C)c(Br)c5)cc4)ncnc3c2)CC1 Show InChI InChI=1S/C29H31BrN6O2/c1-19-3-4-23(15-26(19)30)35-29(37)34-22-7-5-21(6-8-22)33-28-25-10-9-24(16-27(25)31-18-32-28)38-17-20-11-13-36(2)14-12-20/h3-10,15-16,18,20H,11-14,17H2,1-2H3,(H,31,32,33)(H2,34,35,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human GST-tagged VEGFR2 intracellular domain using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 as substrate after 30 mins by HTRF assay				Bioorg Med Chem Lett 22: 110-4 (2011) Article DOI: 10.1016/j.bmcl.2011.11.061 BindingDB Entry DOI: 10.7270/Q2H132FD
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