BDBM50361199 CHEMBL1934330

SMILES: CN1CCC(COc2ccc3c(Nc4ccc(NC(=O)Nc5ccc(Br)cc5F)cc4)ncnc3c2)CC1

InChI Key: InChIKey=NUVLAIWRNGFACE-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361199   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50361199 (CHEMBL1934330) Show SMILES CN1CCC(COc2ccc3c(Nc4ccc(NC(=O)Nc5ccc(Br)cc5F)cc4)ncnc3c2)CC1 Show InChI InChI=1S/C28H28BrFN6O2/c1-36-12-10-18(11-13-36)16-38-22-7-8-23-26(15-22)31-17-32-27(23)33-20-3-5-21(6-4-20)34-28(37)35-25-9-2-19(29)14-24(25)30/h2-9,14-15,17-18H,10-13,16H2,1H3,(H,31,32,33)(H2,34,35,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human GST-tagged VEGFR2 intracellular domain using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 as substrate after 30 mins by HTRF assay				Bioorg Med Chem Lett 22: 110-4 (2011) Article DOI: 10.1016/j.bmcl.2011.11.061 BindingDB Entry DOI: 10.7270/Q2H132FD
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