BDBM50361202 CHEMBL1933080

SMILES: COc1cc2c(Nc3ccc(NC(=O)Nc4cccc(F)c4)cc3)ncnc2cc1OCC1CCN(C)CC1

InChI Key: InChIKey=DCMKNZRIUVAJCP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361202   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50361202 (CHEMBL1933080) Show SMILES COc1cc2c(Nc3ccc(NC(=O)Nc4cccc(F)c4)cc3)ncnc2cc1OCC1CCN(C)CC1 Show InChI InChI=1S/C29H31FN6O3/c1-36-12-10-19(11-13-36)17-39-27-16-25-24(15-26(27)38-2)28(32-18-31-25)33-21-6-8-22(9-7-21)34-29(37)35-23-5-3-4-20(30)14-23/h3-9,14-16,18-19H,10-13,17H2,1-2H3,(H,31,32,33)(H2,34,35,37)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Shenyang Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human GST-tagged VEGFR2 intracellular domain using biotin-aminohexyl-EEEEYFELVAKKKK-NH2 as substrate after 30 mins by HTRF assay				Bioorg Med Chem Lett 22: 110-4 (2011) Article DOI: 10.1016/j.bmcl.2011.11.061 BindingDB Entry DOI: 10.7270/Q2H132FD
					More data for this Ligand-Target Pair