BDBM50361230 CHEMBL1934520

SMILES: COCCS(=O)(=O)c1ccc(cc1)-c1ccc(CCN2CCC[C@H]2C)cc1

InChI Key: InChIKey=PTAZTAQXCREXPY-GOSISDBHSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50361230   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Rattus norvegicus (rat))	BDBM50361230 (CHEMBL1934520) Show SMILES COCCS(=O)(=O)c1ccc(cc1)-c1ccc(CCN2CCC[C@H]2C)cc1 |r| Show InChI InChI=1S/C22H29NO3S/c1-18-4-3-14-23(18)15-13-19-5-7-20(8-6-19)21-9-11-22(12-10-21)27(24,25)17-16-26-2/h5-12,18H,3-4,13-17H2,1-2H3/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of N-[3H]-methylhistamine from histamine H3 receptor in rat cortex membranes				Bioorg Med Chem Lett 22: 71-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.075 BindingDB Entry DOI: 10.7270/Q27M08C7
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50361230 (CHEMBL1934520) Show SMILES COCCS(=O)(=O)c1ccc(cc1)-c1ccc(CCN2CCC[C@H]2C)cc1 |r| Show InChI InChI=1S/C22H29NO3S/c1-18-4-3-14-23(18)15-13-19-5-7-20(8-6-19)21-9-11-22(12-10-21)27(24,25)17-16-26-2/h5-12,18H,3-4,13-17H2,1-2H3/t18-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Arena Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of human ERG by patch-clamp assay				Bioorg Med Chem Lett 22: 71-5 (2011) Article DOI: 10.1016/j.bmcl.2011.11.075 BindingDB Entry DOI: 10.7270/Q27M08C7
					More data for this Ligand-Target Pair