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BDBM50361674 CHEMBL1940917

SMILES: CCNC(=O)c1noc(c1NC(=O)c1sccc1C)-c1cc(Cl)c(O)cc1O

InChI Key: InChIKey=FPGYLUIGKHTKQV-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361674   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
HSP90 and hnRNPA2/B1


(Homo sapiens (Human))
BDBM50361674
PNG
(CHEMBL1940917)
Show SMILES CCNC(=O)c1noc(c1NC(=O)c1sccc1C)-c1cc(Cl)c(O)cc1O
Show InChI InChI=1S/C18H16ClN3O5S/c1-3-20-17(25)14-13(21-18(26)16-8(2)4-5-28-16)15(27-22-14)9-6-10(19)12(24)7-11(9)23/h4-7,23-24H,3H2,1-2H3,(H,20,25)(H,21,26)
PDB
MMDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 74n/an/an/an/an/an/a



Universit£ degli Studi di Ferrara

Curated by ChEMBL


Assay Description
Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assay


J Med Chem 54: 8592-604 (2011)


Article DOI: 10.1021/jm201155e
BindingDB Entry DOI: 10.7270/Q2QF8T9M
More data for this
Ligand-Target Pair