BDBM50361675 CHEMBL1940918

SMILES: CCNC(=O)c1noc(c1NC(C)=O)-c1cc(Cl)c(O)cc1O

InChI Key: InChIKey=WEAJPAPZLYQPRZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361675   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Heat shock protein HSP 90-beta (Homo sapiens (Human))	BDBM50361675 (CHEMBL1940918) Show SMILES CCNC(=O)c1noc(c1NC(C)=O)-c1cc(Cl)c(O)cc1O Show InChI InChI=1S/C14H14ClN3O5/c1-3-16-14(22)12-11(17-6(2)19)13(23-18-12)7-4-8(15)10(21)5-9(7)20/h4-5,20-21H,3H2,1-2H3,(H,16,22)(H,17,19)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Ferrara Curated by ChEMBL					Assay Description Binding affinity to Hsp90 after 4 hrs by fluorescence polarization assay				J Med Chem 54: 8592-604 (2011) Article DOI: 10.1021/jm201155e BindingDB Entry DOI: 10.7270/Q2QF8T9M
					More data for this Ligand-Target Pair