BDBM50361788 CHEMBL1938524

SMILES: Cc1cc(ccn1)C(NC(=O)CCN1CCC(CC1)c1ccccc1)c1ccc(Cl)cc1

InChI Key: InChIKey=NBCDNJZNVVYLHH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50361788   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolylcarboxypeptidase (PRCP) (Homo sapiens (Human))	BDBM50361788 (CHEMBL1938524) Show SMILES Cc1cc(ccn1)C(NC(=O)CCN1CCC(CC1)c1ccccc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C27H30ClN3O/c1-20-19-24(11-15-29-20)27(23-7-9-25(28)10-8-23)30-26(32)14-18-31-16-12-22(13-17-31)21-5-3-2-4-6-21/h2-11,15,19,22,27H,12-14,16-18H2,1H3,(H,30,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of recombinant human PrCP using Mca-Ala-Pro-Lys(Dnp)-OH as substrate measured for 30 mins by continuous fluorometric assay				Bioorg Med Chem Lett 22: 658-65 (2011) Article DOI: 10.1016/j.bmcl.2011.10.060 BindingDB Entry DOI: 10.7270/Q2B56K50
					More data for this Ligand-Target Pair