BDBM50361836 CHEMBL272096

SMILES: CC1CNC(=O)c2cc3ccc(cc3n2C1)C(=O)Nc1cccnc1

InChI Key: InChIKey=PPKZBHWXZJUOKQ-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50361836   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50361836 (CHEMBL272096) Show SMILES CC1CNC(=O)c2cc3ccc(cc3n2C1)C(=O)Nc1cccnc1 |w:1.0| Show InChI InChI=1S/C19H18N4O2/c1-12-9-21-19(25)17-7-13-4-5-14(8-16(13)23(17)11-12)18(24)22-15-3-2-6-20-10-15/h2-8,10,12H,9,11H2,1H3,(H,21,25)(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer-Ingelheim Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of RSK2 phosphorylation by luminescence assay				Bioorg Med Chem Lett 22: 733-7 (2011) Article DOI: 10.1016/j.bmcl.2011.10.030 BindingDB Entry DOI: 10.7270/Q2XW4K7N
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50361836 (CHEMBL272096) Show SMILES CC1CNC(=O)c2cc3ccc(cc3n2C1)C(=O)Nc1cccnc1 |w:1.0| Show InChI InChI=1S/C19H18N4O2/c1-12-9-21-19(25)17-7-13-4-5-14(8-16(13)23(17)11-12)18(24)22-15-3-2-6-20-10-15/h2-8,10,12H,9,11H2,1H3,(H,21,25)(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer-Ingelheim Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of RSK2-mediated CREB phosphorylation in HeLa cells expressing luciferase reporter gene				Bioorg Med Chem Lett 22: 733-7 (2011) Article DOI: 10.1016/j.bmcl.2011.10.030 BindingDB Entry DOI: 10.7270/Q2XW4K7N
					More data for this Ligand-Target Pair