null

SMILES: CC1(C)CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cccnc1

InChI Key: InChIKey=DZZUEPMVAFYJPR-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50361838   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50361838 (CHEMBL1938775) Show SMILES CC1(C)CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cccnc1 Show InChI InChI=1S/C19H18N4O2/c1-19(2)11-21-18(25)16-8-12-5-6-13(9-15(12)23(16)19)17(24)22-14-4-3-7-20-10-14/h3-10H,11H2,1-2H3,(H,21,25)(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer-Ingelheim Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of RSK2 phosphorylation by luminescence assay				Bioorg Med Chem Lett 22: 733-7 (2011) Article DOI: 10.1016/j.bmcl.2011.10.030 BindingDB Entry DOI: 10.7270/Q2XW4K7N
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase alpha-3 (Homo sapiens (Human))	BDBM50361838 (CHEMBL1938775) Show SMILES CC1(C)CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cccnc1 Show InChI InChI=1S/C19H18N4O2/c1-19(2)11-21-18(25)16-8-12-5-6-13(9-15(12)23(16)19)17(24)22-14-4-3-7-20-10-14/h3-10H,11H2,1-2H3,(H,21,25)(H,22,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer-Ingelheim Pharmaceuticals, Inc. Curated by ChEMBL					Assay Description Inhibition of RSK2-mediated CREB phosphorylation in HeLa cells expressing luciferase reporter gene				Bioorg Med Chem Lett 22: 733-7 (2011) Article DOI: 10.1016/j.bmcl.2011.10.030 BindingDB Entry DOI: 10.7270/Q2XW4K7N
					More data for this Ligand-Target Pair