BDBM50362054 CHEMBL3084429

SMILES: [H][C@]12CC[C@]([H])(C[C@H](O)C1)N2Cc1c2c(C)n[nH]c2nc2c(C)cc(OC)cc12

InChI Key: InChIKey=OOOQCFLLXODUKM-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362054   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50362054 (CHEMBL3084429) Show SMILES [H][C@]12CC[C@]([H])(C[C@H](O)C1)N2Cc1c2c(C)n[nH]c2nc2c(C)cc(OC)cc12 |r,TLB:8:7:10:2.3| Show InChI InChI=1S/C21H26N4O2/c1-11-6-16(27-3)9-17-18(19-12(2)23-24-21(19)22-20(11)17)10-25-13-4-5-14(25)8-15(26)7-13/h6,9,13-15,26H,4-5,7-8,10H2,1-3H3,(H,22,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	265	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cAMP from human recombinant PDE10A1 by competitive binding assay				Bioorg Med Chem Lett 22: 235-9 (2011) Article DOI: 10.1016/j.bmcl.2011.11.023 BindingDB Entry DOI: 10.7270/Q2862GWC
					More data for this Ligand-Target Pair