BDBM50362057 CHEMBL1940067

SMILES: Cc1n[nH]c2nc3c(C)cc(Cl)cc3c(CN3CC4CC3CO4)c12

InChI Key: InChIKey=WMMNZISSDPRVMN-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362057   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50362057 (CHEMBL1940067) Show SMILES Cc1n[nH]c2nc3c(C)cc(Cl)cc3c(CN3CC4CC3CO4)c12 Show InChI InChI=1S/C18H19ClN4O/c1-9-3-11(19)4-14-15(7-23-6-13-5-12(23)8-24-13)16-10(2)21-22-18(16)20-17(9)14/h3-4,12-13H,5-8H2,1-2H3,(H,20,21,22)	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]cAMP from human recombinant PDE10A1 by competitive binding assay				Bioorg Med Chem Lett 22: 235-9 (2011) Article DOI: 10.1016/j.bmcl.2011.11.023 BindingDB Entry DOI: 10.7270/Q2862GWC
					More data for this Ligand-Target Pair