Found 4 hits for monomerid = 50362072 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3
(Homo sapiens (Human)) | BDBM50362072
(CHEMBL1940116)Show SMILES CCn1cc(NC(=O)Cn2cc(Oc3ncnc4cc(OC)c(OC)cc34)cn2)cn1 Show InChI InChI=1S/C20H21N7O4/c1-4-26-9-13(7-23-26)25-19(28)11-27-10-14(8-24-27)31-20-15-5-17(29-2)18(30-3)6-16(15)21-12-22-20/h5-10,12H,4,11H2,1-3H3,(H,25,28) | PDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of VEGFR3 phosphorylation by cell based assay |
Bioorg Med Chem Lett 22: 262-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.019
BindingDB Entry DOI: 10.7270/Q24F1R6H |
More data for this
Ligand-Target Pair | |
Receptor-type tyrosine-protein kinase FLT3
(Homo sapiens (Human)) | BDBM50362072
(CHEMBL1940116)Show SMILES CCn1cc(NC(=O)Cn2cc(Oc3ncnc4cc(OC)c(OC)cc34)cn2)cn1 Show InChI InChI=1S/C20H21N7O4/c1-4-26-9-13(7-23-26)25-19(28)11-27-10-14(8-24-27)31-20-15-5-17(29-2)18(30-3)6-16(15)21-12-22-20/h5-10,12H,4,11H2,1-3H3,(H,25,28) | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of FLT3 phosphorylation by cell based assay |
Bioorg Med Chem Lett 22: 262-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.019
BindingDB Entry DOI: 10.7270/Q24F1R6H |
More data for this
Ligand-Target Pair | |
Macrophage colony stimulating factor receptor
(Homo sapiens (Human)) | BDBM50362072
(CHEMBL1940116)Show SMILES CCn1cc(NC(=O)Cn2cc(Oc3ncnc4cc(OC)c(OC)cc34)cn2)cn1 Show InChI InChI=1S/C20H21N7O4/c1-4-26-9-13(7-23-26)25-19(28)11-27-10-14(8-24-27)31-20-15-5-17(29-2)18(30-3)6-16(15)21-12-22-20/h5-10,12H,4,11H2,1-3H3,(H,25,28) | PDB
UniProtKB/SwissProt
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 200 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of CSF1R phosphorylation by cell based assay |
Bioorg Med Chem Lett 22: 262-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.019
BindingDB Entry DOI: 10.7270/Q24F1R6H |
More data for this
Ligand-Target Pair | |
Platelet-derived growth factor receptor beta
(Homo sapiens (Human)) | BDBM50362072
(CHEMBL1940116)Show SMILES CCn1cc(NC(=O)Cn2cc(Oc3ncnc4cc(OC)c(OC)cc34)cn2)cn1 Show InChI InChI=1S/C20H21N7O4/c1-4-26-9-13(7-23-26)25-19(28)11-27-10-14(8-24-27)31-20-15-5-17(29-2)18(30-3)6-16(15)21-12-22-20/h5-10,12H,4,11H2,1-3H3,(H,25,28) | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| CHEMBL
PC cid
PC sid
UniChem
Similars
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
AstraZeneca
Curated by ChEMBL
| Assay Description
Inhibition of PDGFRbeta phosphorylation by cell based assay |
Bioorg Med Chem Lett 22: 262-6 (2011)
Article DOI: 10.1016/j.bmcl.2011.11.019
BindingDB Entry DOI: 10.7270/Q24F1R6H |
More data for this
Ligand-Target Pair | |
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