BDBM50362073 CHEMBL1940117

SMILES: CCn1cc(NC(=O)Cc2cc(Oc3ccnc4cc(OC)c(OC)cc34)[nH]n2)cn1

InChI Key: InChIKey=VSAFHDPEDTWNLQ-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50362073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Focal adhesion kinase 1/vascular endothelial growth factor receptor 3 (Homo sapiens (Human))	BDBM50362073 (CHEMBL1940117) Show SMILES CCn1cc(NC(=O)Cc2cc(Oc3ccnc4cc(OC)c(OC)cc34)[nH]n2)cn1 Show InChI InChI=1S/C21H22N6O4/c1-4-27-12-14(11-23-27)24-20(28)7-13-8-21(26-25-13)31-17-5-6-22-16-10-19(30-3)18(29-2)9-15(16)17/h5-6,8-12H,4,7H2,1-3H3,(H,24,28)(H,25,26)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of VEGFR3 phosphorylation by cell based assay				Bioorg Med Chem Lett 22: 262-6 (2011) Article DOI: 10.1016/j.bmcl.2011.11.019 BindingDB Entry DOI: 10.7270/Q24F1R6H
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50362073 (CHEMBL1940117) Show SMILES CCn1cc(NC(=O)Cc2cc(Oc3ccnc4cc(OC)c(OC)cc34)[nH]n2)cn1 Show InChI InChI=1S/C21H22N6O4/c1-4-27-12-14(11-23-27)24-20(28)7-13-8-21(26-25-13)31-17-5-6-22-16-10-19(30-3)18(29-2)9-15(16)17/h5-6,8-12H,4,7H2,1-3H3,(H,24,28)(H,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of FLT3 phosphorylation by cell based assay				Bioorg Med Chem Lett 22: 262-6 (2011) Article DOI: 10.1016/j.bmcl.2011.11.019 BindingDB Entry DOI: 10.7270/Q24F1R6H
					More data for this Ligand-Target Pair
Macrophage colony stimulating factor receptor (Homo sapiens (Human))	BDBM50362073 (CHEMBL1940117) Show SMILES CCn1cc(NC(=O)Cc2cc(Oc3ccnc4cc(OC)c(OC)cc34)[nH]n2)cn1 Show InChI InChI=1S/C21H22N6O4/c1-4-27-12-14(11-23-27)24-20(28)7-13-8-21(26-25-13)31-17-5-6-22-16-10-19(30-3)18(29-2)9-15(16)17/h5-6,8-12H,4,7H2,1-3H3,(H,24,28)(H,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of CSF1R phosphorylation by cell based assay				Bioorg Med Chem Lett 22: 262-6 (2011) Article DOI: 10.1016/j.bmcl.2011.11.019 BindingDB Entry DOI: 10.7270/Q24F1R6H
					More data for this Ligand-Target Pair
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50362073 (CHEMBL1940117) Show SMILES CCn1cc(NC(=O)Cc2cc(Oc3ccnc4cc(OC)c(OC)cc34)[nH]n2)cn1 Show InChI InChI=1S/C21H22N6O4/c1-4-27-12-14(11-23-27)24-20(28)7-13-8-21(26-25-13)31-17-5-6-22-16-10-19(30-3)18(29-2)9-15(16)17/h5-6,8-12H,4,7H2,1-3H3,(H,24,28)(H,25,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca Curated by ChEMBL					Assay Description Inhibition of PDGFRbeta phosphorylation by cell based assay				Bioorg Med Chem Lett 22: 262-6 (2011) Article DOI: 10.1016/j.bmcl.2011.11.019 BindingDB Entry DOI: 10.7270/Q24F1R6H
					More data for this Ligand-Target Pair