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SMILES: CSc1nc(N)nc(n1)-c1ccc2COCc3cc(Cl)cc1c23

InChI Key: InChIKey=FOCZPIHBQLIHFJ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362219   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Heat shock protein HSP 90-alpha


(Homo sapiens (Human))		BDBM50362219
PNG
(CHEMBL1939369)
Show SMILES CSc1nc(N)nc(n1)-c1ccc2COCc3cc(Cl)cc1c23
Show InChI InChI=1S/C16H13ClN4OS/c1-23-16-20-14(19-15(18)21-16)11-3-2-8-6-22-7-9-4-10(17)5-12(11)13(8)9/h2-5H,6-7H2,1H3,(H2,18,19,20,21)
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Article
PubMed
n/an/an/a 3.40n/an/an/an/an/a



Chugai Pharmaceutical Co., Ltd

Curated by ChEMBL


Assay Description
Binding affinity to N-terminus biotinylated human Hsp90 alpha by surface plasmon resonance assay

Bioorg Med Chem Lett 22: 1136-41 (2012)


Article DOI: 10.1016/j.bmcl.2011.11.100
BindingDB Entry DOI: 10.7270/Q2KH0NS7
More data for this
Ligand-Target Pair