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BDBM50362319 CHEMBL1939950

SMILES: Cc1cc(c(C)cc1Cl)S(=O)(=O)N1C=CNC(=O)[C@H]1CC(=O)N1CCCC[C@@H](C1)N1CCCC1

InChI Key: InChIKey=CSCBVXMNZUGHNW-PZJWPPBQSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362319   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bradykinin B1 receptor


(Homo sapiens (Human))
BDBM50362319
PNG
(CHEMBL1939950)
Show SMILES Cc1cc(c(C)cc1Cl)S(=O)(=O)N1C=CNC(=O)[C@H]1CC(=O)N1CCCC[C@@H](C1)N1CCCC1 |r,c:14|
Show InChI InChI=1S/C24H33ClN4O4S/c1-17-14-22(18(2)13-20(17)25)34(32,33)29-12-8-26-24(31)21(29)15-23(30)28-11-4-3-7-19(16-28)27-9-5-6-10-27/h8,12-14,19,21H,3-7,9-11,15-16H2,1-2H3,(H,26,31)/t19-,21+/m0/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 23.4n/an/an/an/an/an/a



Amgen, Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cells assessed as inhibition of DAK-induced intracellular calcium le...


Bioorg Med Chem Lett 22: 1061-7 (2012)


Article DOI: 10.1016/j.bmcl.2011.11.112
BindingDB Entry DOI: 10.7270/Q22J6CB2
More data for this
Ligand-Target Pair