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SMILES: CCCN1CC[C@H](NC(=O)C[C@H]2N(C=CNC2=O)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C1

InChI Key: InChIKey=KEOASQMTBKNQAT-UXHICEINSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362335   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
B1 bradykinin receptor


(Homo sapiens (Human))		BDBM50362335
PNG
(CHEMBL1939933)
Show SMILES CCCN1CC[C@H](NC(=O)C[C@H]2N(C=CNC2=O)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C1 |r,c:13|
Show InChI InChI=1S/C23H34N4O4S/c1-5-12-26-13-10-20(23(3,4)16-26)25-21(28)15-19-22(29)24-11-14-27(19)32(30,31)18-8-6-17(2)7-9-18/h6-9,11,14,19-20H,5,10,12-13,15-16H2,1-4H3,(H,24,29)(H,25,28)/t19-,20+/m1/s1
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Similars
Article
PubMed
n/an/a 0.510n/an/an/an/an/an/a



Amgen, Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cells assessed as inhibition of DAK-induced intracellular calcium le...

Bioorg Med Chem Lett 22: 1061-7 (2012)


Article DOI: 10.1016/j.bmcl.2011.11.112
BindingDB Entry DOI: 10.7270/Q22J6CB2
More data for this
Ligand-Target Pair