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SMILES: CN1CC[C@H](NC(=O)C[C@H]2N(C=CNC2=O)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C1

InChI Key: InChIKey=JHZHGLJSZGWJNE-MSOLQXFVSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362337   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
B1 bradykinin receptor


(Homo sapiens (Human))		BDBM50362337
PNG
(CHEMBL1939931)
Show SMILES CN1CC[C@H](NC(=O)C[C@H]2N(C=CNC2=O)S(=O)(=O)c2ccc(C)cc2)C(C)(C)C1 |r,c:11|
Show InChI InChI=1S/C21H30N4O4S/c1-15-5-7-16(8-6-15)30(28,29)25-12-10-22-20(27)17(25)13-19(26)23-18-9-11-24(4)14-21(18,2)3/h5-8,10,12,17-18H,9,11,13-14H2,1-4H3,(H,22,27)(H,23,26)/t17-,18+/m1/s1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 0.420n/an/an/an/an/an/a



Amgen, Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cells assessed as inhibition of DAK-induced intracellular calcium le...

Bioorg Med Chem Lett 22: 1061-7 (2012)


Article DOI: 10.1016/j.bmcl.2011.11.112
BindingDB Entry DOI: 10.7270/Q22J6CB2
More data for this
Ligand-Target Pair