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BDBM50362340 CHEMBL1939928

SMILES: Cc1ccc(cc1)S(=O)(=O)N1C=CNC(=O)[C@H]1CC(=O)NC1CCOCC1(C)C

InChI Key: InChIKey=XPTWUGFSVAMCAY-TZHYSIJRSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362340   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Bradykinin B1 receptor


(Homo sapiens (Human))
BDBM50362340
PNG
(CHEMBL1939928)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N1C=CNC(=O)[C@H]1CC(=O)NC1CCOCC1(C)C |r,c:12|
Show InChI InChI=1S/C20H27N3O5S/c1-14-4-6-15(7-5-14)29(26,27)23-10-9-21-19(25)16(23)12-18(24)22-17-8-11-28-13-20(17,2)3/h4-7,9-10,16-17H,8,11-13H2,1-3H3,(H,21,25)(H,22,24)/t16-,17?/m1/s1
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 25.2n/an/an/an/an/an/a



Amgen, Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cells assessed as inhibition of DAK-induced intracellular calcium le...


Bioorg Med Chem Lett 22: 1061-7 (2012)


Article DOI: 10.1016/j.bmcl.2011.11.112
BindingDB Entry DOI: 10.7270/Q22J6CB2
More data for this
Ligand-Target Pair