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SMILES: Cc1ccc(cc1)S(=O)(=O)N1C=CNC(=O)[C@H]1CC(=O)N[C@@H]1CCCc2ccccc12

InChI Key: InChIKey=CUIOWCCRZGUSSJ-NHCUHLMSSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362360   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
B1 bradykinin receptor


(Homo sapiens (Human))		BDBM50362360
PNG
(CHEMBL1939761)
Show SMILES Cc1ccc(cc1)S(=O)(=O)N1C=CNC(=O)[C@H]1CC(=O)N[C@@H]1CCCc2ccccc12 |r,c:12|
Show InChI InChI=1S/C23H25N3O4S/c1-16-9-11-18(12-10-16)31(29,30)26-14-13-24-23(28)21(26)15-22(27)25-20-8-4-6-17-5-2-3-7-19(17)20/h2-3,5,7,9-14,20-21H,4,6,8,15H2,1H3,(H,24,28)(H,25,27)/t20-,21-/m1/s1
PDB

KEGG

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antibodypedia
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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 3.30n/an/an/an/an/an/a



Amgen, Inc.

Curated by ChEMBL


Assay Description
Antagonist activity at human bradykinin B1 receptor expressed in CHO-D-/aequorin cells assessed as inhibition of DAK-induced intracellular calcium le...

Bioorg Med Chem Lett 22: 1061-7 (2012)


Article DOI: 10.1016/j.bmcl.2011.11.112
BindingDB Entry DOI: 10.7270/Q22J6CB2
More data for this
Ligand-Target Pair