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SMILES: CN(CCC(=O)N1CCN(CC1)c1ccncc1)S(=O)(=O)c1cccc2nsnc12

InChI Key: InChIKey=PVPZHDXORJGAOP-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362402   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Muscarinic acetylcholine receptor M1


(Homo sapiens (Human))		BDBM50362402
PNG
(CHEMBL1940136)
Show SMILES CN(CCC(=O)N1CCN(CC1)c1ccncc1)S(=O)(=O)c1cccc2nsnc12
Show InChI InChI=1S/C19H22N6O3S2/c1-23(30(27,28)17-4-2-3-16-19(17)22-29-21-16)10-7-18(26)25-13-11-24(12-14-25)15-5-8-20-9-6-15/h2-6,8-9H,7,10-14H2,1H3
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Article
PubMed
n/an/a>1.00E+4n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Antagonist activity at human muscarinic M1 receptor expressed in CHO cells assessed as inhibition of acetylcholine-induced calcium mobilization by fl...

Bioorg Med Chem Lett 22: 1044-8 (2012)


Article DOI: 10.1016/j.bmcl.2011.11.110
BindingDB Entry DOI: 10.7270/Q2XS5VVC
More data for this
Ligand-Target Pair