BDBM50362715 CHEMBL1939808

SMILES: COc1cc(C)c2nc3[nH]nc(C)c3c(NCC3CN(C)CCO3)c2c1

InChI Key: InChIKey=WRGKRLZCNHYJOI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50362715   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50362715 (CHEMBL1939808) Show SMILES COc1cc(C)c2nc3[nH]nc(C)c3c(NCC3CN(C)CCO3)c2c1 Show InChI InChI=1S/C19H25N5O2/c1-11-7-13(25-4)8-15-17(11)21-19-16(12(2)22-23-19)18(15)20-9-14-10-24(3)5-6-26-14/h7-8,14H,5-6,9-10H2,1-4H3,(H2,20,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Inhibition of recombinant human PDE10A using [3H]cAMP as substrate by scintillation proximity assay				Bioorg Med Chem Lett 22: 1019-22 (2012) Article DOI: 10.1016/j.bmcl.2011.11.127 BindingDB Entry DOI: 10.7270/Q2BV7H3J
					More data for this Ligand-Target Pair