BDBM50362834 CHEMBL493921

SMILES: O=C(OCCc1ccccc1)\C=C\c1ccccc1

InChI Key: InChIKey=MJQVZIANGRDJBT-VAWYXSNFSA-N

Data: 2 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50362834   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldo-keto reductase family member 1B10 (AKR1B10) (Homo sapiens (Human))	BDBM50362834 (CHEMBL493921) Show SMILES O=C(OCCc1ccccc1)\C=C\c1ccccc1 Show InChI InChI=1S/C17H16O2/c18-17(12-11-15-7-3-1-4-8-15)19-14-13-16-9-5-2-6-10-16/h1-12H,13-14H2/b12-11+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminus His6-tagged AKR1B10 expressed in Escherichia coli BL21 DE3 assessed as pyridine-3-aldehyde reduction by sp...				Eur J Med Chem 48: 321-9 (2012) Article DOI: 10.1016/j.ejmech.2011.12.034 BindingDB Entry DOI: 10.7270/Q2TT4RDB
					More data for this Ligand-Target Pair
Beta amyloid A4 protein (Homo sapiens (Human))	BDBM50362834 (CHEMBL493921) Show SMILES O=C(OCCc1ccccc1)\C=C\c1ccccc1 Show InChI InChI=1S/C17H16O2/c18-17(12-11-15-7-3-1-4-8-15)19-14-13-16-9-5-2-6-10-16/h1-12H,13-14H2/b12-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.04E+6	n/a	n/a	n/a	n/a
Muroran Institute of Technology Curated by ChEMBL					Assay Description Inhibition of QD-labeled amyloid beta (1 to 42) (unknown origin) aggregation after 24 hrs by inverted fluorescence microscopic method				Eur J Med Chem 138: 1066-1075 (2017) Article DOI: 10.1016/j.ejmech.2017.07.026 BindingDB Entry DOI: 10.7270/Q23J3GG8
					More data for this Ligand-Target Pair
Aldose reductase (AR) (Homo sapiens (Human))	BDBM50362834 (CHEMBL493921) Show SMILES O=C(OCCc1ccccc1)\C=C\c1ccccc1 Show InChI InChI=1S/C17H16O2/c18-17(12-11-15-7-3-1-4-8-15)19-14-13-16-9-5-2-6-10-16/h1-12H,13-14H2/b12-11+	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Gifu Pharmaceutical University Curated by ChEMBL					Assay Description Inhibition of human recombinant N-terminus His6-tagged AKR1B1 expressed in Escherichia coli BL21 DE3 assessed as pyridine-3-aldehyde reduction by spe...				Eur J Med Chem 48: 321-9 (2012) Article DOI: 10.1016/j.ejmech.2011.12.034 BindingDB Entry DOI: 10.7270/Q2TT4RDB
					More data for this Ligand-Target Pair