BDBM50362895 Lactoflavin::RIBOFLAVIN
SMILES: Cc1cc2nc3c(nc(=O)[nH]c3=O)n(C[C@H](O)[C@H](O)[C@H](O)CO)c2cc1C
InChI Key: InChIKey=AUNGANRZJHBGPY-SCRDCRAPSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Riboflavin-binding protein (Gallus gallus) | BDBM50362895 (Lactoflavin | RIBOFLAVIN) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 350 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Calvin College Curated by ChEMBL | Assay Description Competitive inhibition of chicken riboflavin binding protein by surface plasmon resonance assay | ACS Med Chem Lett 2: 363-367 (2011) Article DOI: 10.1021/ml100296z BindingDB Entry DOI: 10.7270/Q2SX6DP8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Riboflavin-binding protein (Gallus gallus) | BDBM50362895 (Lactoflavin | RIBOFLAVIN) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 6.60 | n/a | n/a | n/a | 7.4 | n/a |
Calvin College Curated by ChEMBL | Assay Description Binding affinity to chicken riboflavin binding protein assessed as dissociation constant at pH 7.4 in 0.1 M phosphate buffer by isothermal titration ... | ACS Med Chem Lett 2: 363-367 (2011) Article DOI: 10.1021/ml100296z BindingDB Entry DOI: 10.7270/Q2SX6DP8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Riboflavin-binding protein (Gallus gallus) | BDBM50362895 (Lactoflavin | RIBOFLAVIN) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 46 | n/a | n/a | n/a | 4.0 | n/a |
Calvin College Curated by ChEMBL | Assay Description Binding affinity to chicken riboflavin binding protein assessed as dissociation constant at pH 4 in 0.1 M NaAc by isothermal titration calorimetric a... | ACS Med Chem Lett 2: 363-367 (2011) Article DOI: 10.1021/ml100296z BindingDB Entry DOI: 10.7270/Q2SX6DP8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Riboflavin-binding protein (Gallus gallus) | BDBM50362895 (Lactoflavin | RIBOFLAVIN) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 34 | n/a | n/a | n/a | 9.0 | n/a |
Calvin College Curated by ChEMBL | Assay Description Binding affinity to chicken riboflavin binding protein assessed as dissociation constant at pH 9 in 0.1 M Tris by isothermal titration calorimetric a... | ACS Med Chem Lett 2: 363-367 (2011) Article DOI: 10.1021/ml100296z BindingDB Entry DOI: 10.7270/Q2SX6DP8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
HSP60/HSP10 (Homo sapiens) | BDBM50362895 (Lactoflavin | RIBOFLAVIN) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of human N-terminal octa-His-tagged HSP60 expressed in Escherichia coli Rosetta(DE3) pLysS/human HSP10 expressed in Escherichia coli Roset... | Bioorg Med Chem Lett 29: 1106-1112 (2019) Article DOI: 10.1016/j.bmcl.2019.02.028 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Riboflavin-binding protein (Gallus gallus) | BDBM50362895 (Lactoflavin | RIBOFLAVIN) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | 5 | n/a | n/a | n/a | 7.4 | n/a |
Calvin College Curated by ChEMBL | Assay Description Binding affinity to chicken riboflavin binding protein assessed as dissociation constant at pH 7.4 in phosphate buffer by isothermal titration calori... | ACS Med Chem Lett 2: 363-367 (2011) Article DOI: 10.1021/ml100296z BindingDB Entry DOI: 10.7270/Q2SX6DP8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
10 kDa chaperonin (Escherichia coli) | BDBM50362895 (Lactoflavin | RIBOFLAVIN) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >1.00E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of Escherichia coli GroEL expressed in Escherichia coliDH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed a... | Bioorg Med Chem Lett 29: 1106-1112 (2019) Article DOI: 10.1016/j.bmcl.2019.02.028 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thiosulfate sulfurtransferase (Homo sapiens) | BDBM50362895 (Lactoflavin | RIBOFLAVIN) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 8.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of native rhodanese (unknown origin) assessed as reduction in rhodanese enzyme activity after 45 mins by Fe(SCN)3 dye based spectrometric ... | Bioorg Med Chem Lett 29: 1106-1112 (2019) Article DOI: 10.1016/j.bmcl.2019.02.028 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
60 kDa chaperonin (Escherichia coli) | BDBM50362895 (Lactoflavin | RIBOFLAVIN) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | >2.50E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of ATPase activity of Escherichia coli GroEL expressed in Escherichia coliDH5alpha incubated for 60 mins using ATP by spectrometric analys... | Bioorg Med Chem Lett 29: 1106-1112 (2019) Article DOI: 10.1016/j.bmcl.2019.02.028 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
10 kDa chaperonin (Escherichia coli) | BDBM50362895 (Lactoflavin | RIBOFLAVIN) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Indiana University School of Medicine Curated by ChEMBL | Assay Description Inhibition of Escherichia coli GroEL expressed in Escherichia coli DH5alpha/Escherichia coli GroES expressed in Escherichia coli BL21 (DE3) assessed ... | Bioorg Med Chem Lett 29: 1106-1112 (2019) Article DOI: 10.1016/j.bmcl.2019.02.028 | |||||||||||
More data for this Ligand-Target Pair |